In a joint project, groups at Tokai University, Tohoku University and Osaka University have synthesized an insulin analog where one of the disulfide bonds linking the A- and B-chain is replaced by diselenide bonds („seleno-insulin“). X-ray analysis revealed a similar...
The target is on improved production of industrial materials by microorganisms, and the topics are clustered around substance production technology (Design), high-speed DNA synthesis / evaluation technology (Build), non destructive / minimally invasive cell evaluation...
In a preclinical study lasting two years, the group of Jun TAKAHASHI at Kyoto University’s CiRA transplanted human iPS cell derived dopaminergic neurons into 7 Macaca monkeys treated with the neurotoxin MPTP, as a Parkinson disease (PD) model. Video-observations and...
Nippon Tect Systems is developing a diagnostic support system for dementia using AI. Currently, doctor’s dementia examination is performed using quantitative data such as neuropsychological examination and image analysis (MRI), and qualitative indicators such as...
Nippon Shinyaku had developed long-strand DNA synthesis in the late 1990ies and started collaboration with the National Center for Mental and Neurological Medicine to develop an antisense RNA (NS-065/NCNP-01) with exon skipping action against DMD. The synthetic...
