A team around CA Vacanti at Harvard Medical School and researchers at RIKEN’s Institute for Developmental Biology in Kobe have found that mouse lymphocytes can be turned into pluripotent cells after a short stress at lowered pH. STAP cells (for stimulus-triggered...
UDP glucuronosyltransferase (UGT1A1) is a metabolic enzyme important in the medication with irinotecan, a DNA topoisomerase I inhibitor and drug used for the treatment of lung or colon cancer. In patients with UGT1A1*6 and UGT1A1*28 genotype, there is a possibility...
Using pathway engineering in cyanobacteria (Synechocystis sp.), a production efficiency of > 14 % based on CO2 supply was achieved. Addition of acetate increased PHA accumulation to 41 %. Nyok-Sean LAU et al., PlOS One, DOI: 10.1371/journal.pone.0086368