Month: January 2014

US-RIKEN team develops pluripotent stem cells by transient low-pH triggered stress, STAP cells

A team around CA Vacanti at Harvard Medical School and researchers at RIKEN’s Institute for Developmental Biology in Kobe have found that mouse lymphocytes can be turned into pluripotent cells after a short stress at lowered pH. STAP cells (for stimulus-triggered acquisition of pluripotency) could be expanded in vitro and, if injected into blastocysts, efficiently […]

Arkray Co. releases kit for rapid detection of UGT1A1 SNPs, a marker for personalized anticancer drug tolerance

UDP glucuronosyltransferase (UGT1A1) is a metabolic enzyme important in the medication with irinotecan, a DNA topoisomerase I inhibitor and drug used for the treatment of lung or colon cancer. In patients with UGT1A1*6 and UGT1A1*28 genotype, there is a possibility that due to a decrease in enzyme activity , serious side effects such as diarrhea […]

Shindo Co. develops seamless LED-bearing “electronic textiles”, outdoor applications

Shindo Co., a textile company located in Fukui Prefecture, has developed textiles incorporating soft LED ribbons. The textiles contain very soft ribbon-wired LEDs manufactured through a MEMS processing technology which ensures softness, water and heat protection. The textiles are proposed for sportsware applications. JST news release, January 21, 2014

RIKEN team visualizes timeline of events in chloroplast during photosynthesis

Using the moss Physcomitrella patens as a model organism and a fluorescence confocal laser microscope as a tool, the time-resolved structural changes of thylakoid membranes during illumination were observed. Iwai, M., Yokono, M., Nakano, A. "Visualizing structural dynamics of thylakoid membranes" Scientific Reports, 2014, doi: 10.1038/srep03768

Tsukuba group elucidates mechanism for aggravation of allergic diseases upon disturbance of gut bacteria by antibiotic ingestion

Using a transgenic mouse system, the group of Professor Akira SHIBUYA of Tsukuba University has found that gut dysbiosis initiated by dosing antibiotics and leading to fungal growth in the intestine promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2 JST news release, January 16, 2014

Scroll to top