18-11 Green Earth Institute uses Corynebacterium resting cells to prepare green chemicals from formaldehyde
In an artificial metabolic system, the formaldehyde is added via aldolase, to appropriate cosubstrates forming 2,4-dihydroxybutyric acid (DHB), homoserine (hSer), and 1,3-propanediol (PDO). As an aldolase, hpal from Escherichia coli was used. It accepts also other aldehydes. The study is considered a proof of principle that high-cell density cultures of resting cells of C. glutamicum […]