Window to Japan
The program is clustered around Professor Takashi YAMAMOTO who has developed artificial nucleases (TALEN and ZFN), chimera proteins whose domains are specifically combined with restriction enzyme FokI. If it combines with the target sequence, DNA will be cut. Since selection of a target sequence is possible, this method is considered as next-generation KO technology, which […]
The test strain, Bifidobacterium longum (APS001F) which expresses adenosine deaminase (AD), will be administered intravenously followed by 5-fluorocytosine, leading to selective formation of highly toxic 5-fluorouracil in anaerobic environments where tumor tissue is located. The patient is also given maltose, a growth factor for Bifidobacteria. Experiments on mice and rats in Japan led to a […]
Profs. Hiroshi NAGASHIMA and others report that transfer of swine blastomeres to transgenic swine embryos defunct in pancreas formation led to healthy swines carrying a normal pancreas. This study is part of the ERATO “Nakauchi stem cell control project” financed by the JST. Hitomi MATSUNARI et al., PNAS doi:10.1073/pnas.1222902110
The company will be jointly financed by Daiichi Sankyo and Mitsubishi UFJ Capital. Technology is based on an antisense oligonucleotide (an ethylene-bridged nucleic acid) which acts by exxon skipping. The target period for clinical proof of concept is 4 years. Daiichi Sankyo press release, February 14, 2013
The increase is for mostly for industrialization of research results from universities through public private partnerships. Regenerative medicine and the industrialization of iPS cell technology will be strongly supported Nikkei Biotech, February 13, 2013
Nikkei Biotech, February 13, 2013
The prebiotic is produced by Aspergillus fermentation in a salt-free surface medium on a defatted soybean substrate and sold as antiallergic material Nichimo Biotechs press release, February 12, 2013
Whereas there are several examples in Japanese Pharmaceutical Industry were orphan drugs with a clear indication have been developed, pricing schemes are still not finally concluded with the National Health Insurance scheme, and the present discussion of a 20 % higher price might not be enough to cover additional costs Nikkei Biotech, February 12, 2013
The polyphenols originate from green coffee bean extracts Nestlé Japan website https://nestle.jp/brand/grn/
Prof Juichi YAMAGIWA, Kyoto Prefectural university, has screened and characterized a new species of Bifidobacterium from the excrements of a herd of about 20 Western lowland gorillas in Gabon. Genetic analysis revealed that this species might be phylogenetically older compared to Bifidobacteria species in the human gut. Nikkei Journal, February 8, 2013