In a preclinical study lasting two years, the group of Jun TAKAHASHI at Kyoto University’s CiRA transplanted human iPS cell derived dopaminergic neurons into 7 Macaca monkeys treated with the neurotoxin MPTP, as a Parkinson disease (PD) model. Video-observations and MRI- and PET-imaging showed that PD symptoms were reduced over time, as compared to 3 controls. The team is now peparing a doctor-initiated clinical trial in the autumn of 2018.

CiRA news release, August 31, 2017