Month: June 2013

MHLW gives green light for clinical research on iPS studies to treat age-related macular degeneration

The studies will be done by Masayo TAKAHASHI of RIKEN’s Center for Developmental Biology in Kobe. Age-related macular degeneration concerns up to 700.000 elderly Japanese. It is planned to create autologous iPS cells using skin cells taken from a patient, and then induce retinal pigment epithelium cells, or RPE cells, from each patient’s iPS cells. […]

RIKEN team develops procedure for making tissues transparent without damage

Dr Takeshi IMAI and others at RIKEN Center for Developmental Biology in Kobe have developed a fructose-based solution which rendered mouse embryos and brains transparent within 3 days, permitting observations of fine structures and flurescent labeling under a flurescence microscope without making sections Meng-Tsen KE et al., Nature Neuroscience 2013,doi: 10.1038/nn.3447

JCR Pharmaceuticals, Kobe, opens first plant for pharmaceuticals production based on disposable bioreactors

Japan Chemical Research Co. has completed a plant with up to three culture vessels containing 2.000 L volume each, to be used to produce recombinant therapeutic enzymes. The product pipeline includes human iduronate 2-sulfatase for the treatment of Hunter’s disease, human alpha-galactosidase A for the treatment of Fabry’s-disease, and human glucocerebrosidase for the treatment of […]

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