Month: September 2016

Nagase and Hayashibara market first joint product, an enzyme preparation for bread baking

The enzyme product Denabeiku Extra”, an exo maltotetrahydrolase OH hydrolase (G4 generating enzyme) produced by Pseudomonas stutzeri, increases bread volume during baking. The enzyme is similar to a recombinant enzyme from B. subtilis introduced by Danisco Japan but does not require recombinant technology for production.” Nagase news release,

Toray develops nanoalloy”, a designer polyamide”

The new slide-ring polymer is based on polyrotaxanes, ring-shaped molecules which are penetrated by string-like molecules having structures such as rosary and necklaces. The resulting polymer has a 6 times improved breakage stability and a 20 times improved bending durability compared to conventional polyamides. The concept was developed under JST’s impact program JST news release, […]

Nitta Gelatine develops Cellmatrix, a collagen for use in cell expansion

The low endotoxin type product has already been used in various protocols for cell expansion. It is derived from porcine and bovine tendons and eye lenses. In 2016, a cell trnasport system at ambient temperatures using gelatin gel was developed, reducing vibration during transportation. In RIKEN Kobe’s Masayo Takahashi clinical studies on autologous iPS cell-derived […]

RIKEN-Keio team resolves molecular mechanism of phototropin, plants’ blue light receptor protein

Using the SPring-8 synchrotron facility which allows the rapid determination of minute structural changes by small-angle x-ray scattering, the researchers elucidated the mechanism of this complex kinase. The 1000 amino acid protein complex phototropin consists of two domains LOV1 and LOV2 of which each contains an FAD residue. If LOV2 receives blue light, the signal […]

RIKEN team achieves iPS cell-derived retinal cell transplantation without immune rejection using HLA matching

The group of Tadashi SUGITA prepared iPS cells from homozygeous cynomolgus monkeys. Retinal pigment epithelial cells (RPE cells) derived from these iPS cells were transplanted into the retina of the other cynomolgus monkeys. Only if the MHC type of donors and recipients was matched, no rejection was observed after six months. In-vitro experiments with human-derived […]

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