Japan’s hyper-aging society will have enormous effects on industry, medical services, nursing etc. The JST-supported project carried out by Chiba University allows a preview on 2040 for the consequences of population decline for each prefecture. JST news release, October 30, 2017
Toyota commercializes „GRAS-Di“ DNA marker technology which facilitates marker breeding
In cooperation with Kazusa DNA Research Institute, Eurofins and Genebay, Toyota will commercialize this technology developed in its Bioresearch Institute in Miyoshi. The technology is based on Genotyping by Random Amplicon Sequencing and allows the genetic screening of thousands of breeding variants of plants or animals at low cost. It was already successfully applied to […]
RIKEN team develops fluorescent probe that visualizes the complete cell cycle in real time
The groups of Atsushi MIYAWAKI and Asako SAKAGAMI at RIKEN have developed an improved flurescent probe (FUCCI (CA) ) whose fluorescence differs once a cell is in phase S, G2 or M phase of its cell cycle. The technology is based on cell-cycle dependent ubiquitin-mediated proteolysis and can be applied to observe the life cycles […]
RIKEN group develops novel pathway to maleic acid in E. coli
The group of Akihiro KONDO at RIKEN has used synthetic biology to produce maleic acid from glucose in recombinant E. coli by a novel pathway. The research team combined 3-hydroxybenzoic acid synthetase (Hyg5) derived from Streptomyces hygroscopicus, 3-hydroxybenzoic acid 6-hydroxylase (3HB6H) derived from Rhodococcus jostii RHA, and maleyl pyruvate synthase (MPS) from Rhodococcus sp. NCIMB […]
JCR Pharma develops proprietary technology for treatment of Hurler syndrome
Hurler syndrome (mucopolysaccharidosis type I) is a lysosomal storage disorder characterized by deficiency of a specific enzyme, alpha-L-iduronidase, responsible for the degradation of glycosaminglycans (GAGs), and results in excessive buildup of GAGs throughout the body, leading to symptoms also in the central nervous system (CNS). JCR has developed technology to penetrate the blood-brain barrier (J-Brain […]
RIKEN team finds model for improved treatment of acute myelogenous leukemia
Acute lymphocytic leukemia is common in children, while acute myelogenous leukemia is more common in adults and has a higher recurrence rate. A RIKEN group around Fumihiko ISHIKAWA has found in experiments with humanized mice (non-immune mice to which human progenitor cells with a mutation in the FLT3 gene were transplanted, leading to the onset […]
„Future hyrogen society“: NEDO-supported team develops non-fluorine electrolyte membrane for fuel cells
Kenji MIYATTI of the University of Yamanashi and colleagues have developed a high performance non-fluorine-based electrolyte membrane for fuel cells based on polyphenylene electrolyte (SPP – QP). The membrane has excellent chemical durability and provides fuel cells with initial power generation characteristics equivalent to those of current fluorinated electrolyte membranes. At present, fluorinated electrolyte membranes […]
NEDO-supported group develops blue-laser 3D printer for pure copper
In the NEDO project, Osaka University’s group of Professor Masahiro Tsukamoto, collaborating with Shimadzu Co., Nichia Corporation and Muratani Machinery Works has developed a blue-laser 3D printer that can print layers of pure copper by a laminating high-quality blue semiconductor laser. This technology will be applied to process parts for aerospace, space and electric car […]
NEDO starts desalination project in Qatar, using coolant seawater
In the project, seawater used in Ras Laffan industrial city as cooling water for facilities and discharged to the sea at a maximum of about 45 ° C will be used as the water resource for seawater desalination by a reverse osmosis membrane process developed in Japan. It is expected to save 80% or more […]
Toyobo and Human Metabolome Technologies (HMT) develop enzyme kit for depression biomarker
Research by HMT and others has revealed that the concentration of ethanolamine phosphate (PEA) in blood fluctuates according to the medical condition of depression, suggesting its utility as a biomarker to support depression diagnosis. HMT has developed an enzyme kit for PEA detection, and Toyobo will provide suitable enzymes such as ethanolamine phosphate lyase. Toyobo […]