Month: January 2017

Takara Bio starts domestic phase II of oncolytic virus HF10

In this study, Takara Bio will evaluate the effectiveness, safety, immunological tests etc. when HF 10 and ipilimumab are administered concomitantly for the treatment of unresectable or metastatic malignant melanoma. HF10 is an attenuated strain of Herpes Simplex Virus Type 1 (HSV-1) and shows a remarkable antitumor effect when injected into the cancer locus. Takara […]

Hiroshima University group identifies targets for leukemia treatment using CML stem cells

Chronic myelogenous leukemia (CML) might be treated by drugs that inhibit the dipeptide transporter Slc15A2 – a finding based on metabolomic and transciptomic studies by the group of Nakahito NAKAHIRO at Hiroshima University’s A-bomb Radiological Science Institute. Drugs targeting this transporter might help to treat CML patients who have become resistant to tyrosine kinase inhibitors. […]

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