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Mitsubishi’s Life Science Institute (LSI) will start clinical trial on treatment of spinal cord injury with Muse cells

LSI announced that a domestic clinical trial for spinal cord injury in the subacute phase will be started using the Muse cell product “CL2020”.. The company has been conducting clinical trials already for three other diseases, acute myocardial infarction, cerebral infarction, and epidermolysis bullosa, and aims to apply for approval in 2020 and 2021 for any of the four diseases. Muse cells are pluripotent stem cells discovered by Prof. Mari Dezawa of Tohoku University. They occur in mesenchymal stem cells (MSC) of bone marrow and other organs, and they can differentiate into any ectoderm, mesoderm or endoderm. They can be stored through cryopreservation.

Mitsubishi LSI news release, July 10, 2019

 

EdiGene startup to focus on gene therapy of orphan diseases

The company is a spin-off of the University of Tokyo, using the research results of Osamu NUREKI. They develop in vivo gene therapy using adeno-associated virus (AAV) vectors for single gene diseases. https://www.j-startup.go.jp/en/startups/017_edigene.html

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