Year: 2019

Japan’s government tries to popularize genome editing by a “BioStation” website

The website https://bio-sta.jp/contains information on latest breeding results and explains in much detail the technology behind these results. Projects include deletion of target genes which result in tomatoes with high GABA content, potatoes without solanine, and red sea bream with enhanced muscle meat (myostatin knock-out). The secretariat of BioStation is located at the Japan Agriculture, Forestry […]

COTO LABO consortium strives for better life science data

Eight companies have joined Shimadzu Corporation in an attempt to obtain better reproducible data in the life sciences such as drug-related research. 53 ring tests among these companies had shown that reproducibility of data was indeed low. 8 companies (iPS Portal, Earth Environment Service, NTT DATA, Olympus, Kataoka Manufacturing, Taisei Corporation, Hitachi Industrial Equipment Systems, […]

NEDO consortium improves microbial bioproduction by AI

In this project, it is planned to build a data infrastructure system for collecting and sharing data which correlate optical and electrochemical sensor data that have not yet been used at bio-production sites (bioproduction management using convolutional data). An AI system will be developed that predicts the optimal culture method hitherto not possible with human […]

Genome editing provides high-sugar content tomatos: Nagoya University

Katsuhiro SHIRATAKE of Nagoya University and coworkers from RIKEN have achieved the development of a high-fructose tomato by disrupting the INVINH gene, encoding an invertase inhibitor. As genome editing tools, a CRISPR / Cas9 vector and Target-AID vector targeting INVINH were used. In some  transformants, the increase in sugar content was up to 2fold. Lecture at […]

Cellulose nanofibers one step closer to wide industrial use: NEDO, Japan

NEDO has announced that acetylated ligno cellulose nanofiber (CNF) show high biodegradability (~90% in the OECD TG301C test), bringing this material closer to wide applications. CNF are cellulose fibers with a diameter of 3 – 10 nm obtained from woody biomass such as bamboo or other wood. They are already produced by companies such as […]

JBA’s Bioindustry Award 2019 goes to Kaneka and RIKEN researchers for the development of a PHBH polymer biodegradable on soil and in seawater

The poly-hexanoate-butyrate (PHBH) copolymer is produced by Kaneka from plant oil using a recombinant strain of Cupriavidus necator at a capacity of currently 1,000 tons, with plans to increase production to 5,000  and later to 100,000 tons a year. PHBH materials decompose not only on soil, but also in seawater (90% within 6 months at 30°C) and […]

Japan to create its bioeconomy from “bio-digital integration” (バイオとデジタルの融合)

The term will serve as a unifying concept leading to “smart cells” of plants and microorganisms by combining genome analysis, genome editing and metabolic engineering of cells supported by robotics, cloud computing, big data informatics and artificial intelligence.  These technologies will allow to modify living cells and improve genomic selection for a wide range of applications […]

Mitsubishi’s Life Science Institute (LSI) will start clinical trial on treatment of spinal cord injury with Muse cells

LSI announced that a domestic clinical trial for spinal cord injury in the subacute phase will be started using the Muse cell product “CL2020”.. The company has been conducting clinical trials already for three other diseases, acute myocardial infarction, cerebral infarction, and epidermolysis bullosa, and aims to apply for approval in 2020 and 2021 for […]

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