Long QT syndrome (LQTS) is an arrhythmogenic disorder that can lead to sudden death. Using whole exome sequencing analysis of 59 LQTS and 61 unaffected individuals in 35 families and 138 unrelated LQTS cases, 92 candidate mutations in 88 genes for 23 of the 35 families were identified.
RIKEN news release, July 3, 2015
RIKEN group finds candidate genetic mutations for long QT syndrome