The team of Atsushi TANAKA used iPS cells from healthy and diseased patients and differentiated them into cardiomyocytes. It was shown that differences in endothelin-1 formation are involved in pathogenesis and a more detailed pathogenetic picture emerged.
JST news release, Nov. 18, 2014
Team at Keio University clarifies pathology of hypertrophic cardiomyopathy using iPS technology