After developments and tests since 2007, Terumo has now applied for the manufacture and marketing of skeletal myoblast sheets for the treatment of ischemic heart disease. Muscle tissue from the thigh of a patient is collected, and tissue is cultured in vitro to sheets which are pasted on the damaged surface of the myocardium. As the cells are taken from the patient, there is no immunorejection.
Terumo news release, Oct. 31, 2014
Terumo Co. applies to MHLW for approval of skeletal myoblast sheets, world’s first myocardial regenerative medicine