The group around Hiroki UEDA found that the use of amino alcohols elutes blood heme in whole organisms promoting tissue bleaching. This allowed for the development of a whole organism imaging method showing systemic and organ systems at one cell resolution. By establishing a method to capture the whole organ or body as a three-dimensional image, the procedure can be applied to 3D pathology analysis and anatomy.
JST news release, November 7, 2014
RIKEN QBiC develops method to display transparent organs or laboratory animals at 1 cell resolution