https://bio.nikkeibp.co.jp/atcl/news/p1/23/07/05/10883/

Hyperion FoodTech (Nara City, President Kazuhiro Takekita), a company involved in the research and development of new food materials such as cultured meat, announced the establishment of pluripotent stem cells (ES cells) from fertilized embryos from domestic cattle. Bovine ES cells will be differentiated into bovine skeletal muscle cells, which will be used to produce cultured meat. The company plans to conduct joint research with companies and provide bovine ES cells for a fee. Currently, most cultured meat is produced from bovine muscle tissue, from which skeletal muscle cells and other cells are cultured. It is estimated that 8 x 1013 cells can be cultured from 100 g of bovine muscle tissue, which is equivalent to 70 kg of cultured meat. If the cells are derived from bovine ES cells, theoretically, 1 x 106 bovine ES cells can grow to 7 x 1014 cells, which is equivalent to 700 kg of cultured meat.

Hyperion has established conditions for culturing bovine fertilized embryos until they grow into blastocysts, the conditions for culturing internal cell clusters, and other factors, and also developed an optimal composition for the culture medium. The company has just applied for a patent on its method for establishing bovine ES cells.