https://bio.nikkeibp.co.jp/atcl/news/p1/25/11/20/13999/

Grand Green, a Nagoya-based company specializing in crop breeding, registered “GG-T1” tomato, which has increased sugar content through genome editing, as a food product. This brings the total number of genome-edited foods registered in Japan to 10.

In addition to developing genome-edited crops in-house, the company also provides genome editing technology to seed distributors and food companies through collaborative research. For GG-T1, the company apparently deleted the function of the inhibitor gene (INVINH1) of the enzyme “invertase,” which catalyzes the reaction that hydrolyzes sucrose into fructose and glucose to provide sugar to the fruit, in a medium-sized cultivar developed in-house. According to the published materials, the CRISPR/Cas9 system was introduced using a particle gun, causing a 28-base deletion. It has been confirmed that genome editing does not result in the creation of new allergens or toxic substances.