Tohoku University Tohoku Medical Megabank Organization (ToMMo) announced on June 30, 2022, that it has completed the analysis of the whole genome information of 50,000 Japanese. The Tohoku Medical Megabank has accumulated health information and biological samples of 150,000 local residents, mainly in Miyagi and Iwate prefectures, and ToMMo is currently analyzing them. ToMMo plans to eventually analyze the whole genome information of 100,000 people, ToMMo established a “Consortium for Integrated Analysis of Whole Genome Information and Medical/Health Information” with five pharmaceutical companies. The participating companies are Eisai, Ono Pharmaceutical, Takeda, Daiichi Sankyo, and Janssen Pharma. ToMMo has been promoting genome analysis using consortium fees and public funds obtained from pharmaceutical companies. First, the consortium will release the genome information for 50,000 people to participating companies, and after a certain period of time, the information will be made available to nonconsortium members as well.
ToMMo also released a whole genome reference panel for 38,000 individuals that includes the location and frequency of gene sequence mutations. The analyzed data can be found on the website of the Japanese Multilayer Omics Reference Panel (jMorp). At present, information on the allele frequencies of SNV and INDEL on autosomal chromosomes is available, and information on the frequencies of X chromosome and mitochondrial variants is expected to be made available at a later date.