In collaboration with Bonac Co., the team of Masahiko KURODA at Tokyo University of Medicine has developed a single-stranded RNA (“miR-29b Psh-match) that has a unique structure to avoid problems associated with the therapeutic uses of miRNAs. A comparison of miR-29b Psh-match and double-stranded miR-29b mimic indicated that the single-stranded form was significantly more effective towards fibrosis according to both in vivo and in vitro experiments in mice.

Nikkei Biotech news release, February 28, 2017