Professor Hiroki NANBA of Hamamatsu Medical University explores the use of Muse cells (multi-lineage differentiating stress enduring cell) as a carrier for suicide genes that migrate into glioma (brain) tumor cells. The strategy is based on administration of ganciclovir with recombinant Muse cells transfected with HSV-TK gene with lentiviral vector. The Muse cells are previously isolated from patients with glioma.
Nikkei Biotech news release, January 10, 2017
Hamamatsu University scientist explores suicide gene therapy using Muse cells