Koji YONEKURA and colleagues at RIKEN’s SPring-8 center have developed a software ScatCurve which allows to determine the optimum value of partial charges on each atom in a protein. Once applied to the analysis of catalase microcrystal by electron beam analysis or to cryo-electron microscopic images of ß-galactosidase, the charge distribution in either protein could be precisely determined.

RIKEN news release, August 25, 2016