Koji YONEKURA and colleagues at RIKEN’s SPring-8 center have developed a software ScatCurve which allows to determine the optimum value of partial charges on each atom in a protein. Once applied to the analysis of catalase microcrystal by electron beam analysis or to cryo-electron microscopic images of ß-galactosidase, the charge distribution in either protein could be precisely determined.
RIKEN news release, August 25, 2016
RIKEN team improve structural analysis of proteins by scattering refinement software