D-psicose, the 3-epimer of D-fructose, has nearly 0 calories and about 70 % of saccharose sweetness. Kyowa has reported on a high efficiency production process (29 g/L) based on self-cloning in E. coli
JSBBA Sapporo, Poster 4F046, March 30, 2016
Kyowa Hakko Bio succeeds in D-psicose production from glucose using engineered E. coli