RIKEN’s SACLA achieves protein 3D structure determination using X-ray free-electron laser

The method was proven by using microcrystals of an enzyme of unknown structure, luciferin-regenerating enzyme(308 amino acids), and its analogs with heavy atom isomorphous replacements. Only 20,000 patterns in total recorded at room temperature were needed for phasing.

RIKEN news release, September 14, 2015

RIKEN’s SACLA achieves protein 3D structure determination using X-ray free-electron laser
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