Group at RIKEN Bioresource Center finds procedure to stabilize mouse epiblast stem cells

When inhibitors for Wnt-signaling such as IWP-2 were added to the growth medium, the epi stem cells could be stably maintained in a “primed” pluripotent state, and directly and in good yields differentiated from the primed state.

Michihiko SUGIMOTO et al., Stem Cell Report available online 26 March 2015

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