The laboratory of Isao YONEKURA has reported on a new technology which, if applied to thin crystals of, e. g., membrane proteins, allows visualization of the charge state of amino acids and ions. When applied to very thin three-dimensional crystals of rabbit sarcoplasmic reticulum Ca2 + -ATPase or bovine liver catalase, the electrostatic potential map of the active site of these proteins could be visualized.

RIKEN news release, Feb. 23, 2015