A team around Takahiko SATO identified miR-195 and miR-497 to induce cell cycle arrest in adult skeletal muscle. Transplantation of cultured MuSCs treated with miR-195/497 contributed to regenerating muscles of dystrophin-deficient mice, indicating the potential utility of miR-195/497 for stem cell therapy of muscular dystrophy.
China Bio news release, August 18, 2014
iCeMS and CiRA team induces mouse skeletal muscle stem cells with miRNA, potential for treatment of muscular dystrophy