The pig kidney amino acid racemase was modified by directed evolution to provide only the desired enantiomer. α-Methylbenzylamine is an important synthone, e. g., for the synthesis of thalidomide
JST news release, February 7, 2014
Asano ERATO project group develops R-specific amino acid oxidase, deracemization of α-methylbenzylamine with high enantioselectivity